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VACCINES

Germany’s BioNTech hopes for 12-15 year olds to receive Covid vaccine from June

BioNTech said Thursday that it expected its Covid-19 vaccine, jointly developed with Pfizer, to be available to 12-to-15-year-olds in Europe from June.

Germany's BioNTech hopes for 12-15 year olds to receive Covid vaccine from June
A pupil at a school in Cologne doing a rapid test. Photo: DPA

The German firm’s CEO Ugur Sahin told Der Spiegel weekly that it was “in the final stretches” of preparing its submission for European regulatory approval.

The evaluation of the trial data “takes four to six weeks on average”, he added.

Vaccinating children is seen as a crucial next step toward herd immunity and ending the pandemic.

The prospect of getting older children inoculated before the next school year starts would also relieve the strain on parents who are juggling the demands of homeschooling while keeping up with jobs.

“It’s very important to enable children a return to their normal school lives and allow them to meet with family and friends,” Sahin told Spiegel.

READ ALSO: German doctors call for faster vaccination of young people

BioNTech/Pfizer already applied for emergency US authorisation of their jab for 12 to 15-year-olds earlier this month.

Sahin expects to submit a similar request to the European Medicines Agency (EMA) next Wednesday, he told Spiegel.

The move comes after BioNTech and Pfizer in late March announced that phase 3 clinical trials of their vaccine for children aged 12-15 showed it was 100 percent effective in warding off the disease.

Both companies are also racing to get the jab approved for younger children, from six months upwards.

“In July, the first results for five to 12-year-olds could be available, and those for younger children in September,” he said.

Ongoing trials so far are “very encouraging”, Sahin said, suggesting that “children are very well protected by the vaccine”.

BioNTech was founded in Mainz by husband and wife team Ugur Sahin and his wife Özlem Türeci. They teamed up with US pharma company Pfizer to produce the shot which is based on novel mRNA technology, and was the first Covid-19 jab to be approved in the West late last year.

‘Immense stress for children’

Calls have been growing to vaccinate children in Germany as soon as possible.

Although no scientifically proven data is available yet, studies suggest that children suffer significantly more from long-term psychological effects than adults, because they lack social contacts more.

According to a representative online survey by the University Medical Center Hamburg-Eppendorf, 40 percent of the 11 to 17-year-olds stated that their quality of life had deteriorated during the pandemic, 44 percent complained of sleep disorders and a third of depression.

Children from poor and socially disadvantaged households are particularly affected. During the coronavirus pandemic, violence in families also appears to have increased – especially in areas where problems existed before.

READ ALSO: ‘More young people will become ill’: Germany facing tough battle against Covid-19 variants

“The level of stress is high and the psychological strain for children is immense,” founder of the Arche children’s project, Bernd Siggelkow told DPA.

Member comments

  1. What about the 30 to 60 year olds. Yes children are important and the elderly are important But honestly the 30 to 60 year old need to get back to Norma life as well. I haven’t seen my children in 2 years. Time to get enough vaccine for all and open up the vaccine centers. Time for mass vaccinations. Germans and all Europeans have waited long enough!!!!!! Rant done ✅

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HEALTH

Italy to step up test-and-trace and sequencing as concern grows about Delta virus variant

The Italian health ministry on Friday told local authorities to increase their coronavirus variant sequencing and tracing efforts, as new data confirmed that the Delta strain is spreading in Italy.

Italy to step up test-and-trace and sequencing as concern grows about Delta virus variant
Photo: Marco Bertorello/AFP

The ministry sent out the instruction in a circular after the Higher Health Institute (ISS) released new figures on Friday showing that the number of infections in Italy caused by the Delta and Kappa variants have increased by 16.8 percent in June.

“From our epidemiological surveillance, a rapidly evolving picture emerges that confirms that also in our country, as in the rest of Europe, the Delta variant of the virus is becoming prevalent,” said Anna Teresa Palamara, director of ISS’s infectious diseases department.

READ ALSO: Italian health experts warn about Delta variant as vaccine progress slows

According to ISS data published on Friday, the SARS-CoV-2 variant prevalent in Italy was found to be the Alpha variant (B.1.1.7), responsible for 74.9 of cases. This is now also the most prevalent globally.

Cases associated with Kappa and Delta variants (B.1.617.1/2) “are few overall in January to June”, the ISS report added. But it stated that the frequency and spread of these reports has “rapidly” increased across the country.

The new ISS figure  still lower than those from independent analysis of data from the virus-variant tracking database Gisaid, which estimated on Thursday that Delta now accounts for as much as 32 percent of recently confirmed new cases.

Several regions have already reported clusters of the Delta variant, though the amount of test result sequencing and analysis carried out by local health authorities in Italy varies and is often low.

Each region currently volunteers to do a certain number genetic sequencing of positive swabs, which means that Italy has less data available about the spread of variants than countries where sequencing is more widespread and systematic, such as the UK or Denmark.

The region of Puglia on Friday confirmed it would begin sending 60 test results per week for further analysis following the health ministry’s instruction.

Italian authorities had largely dismissed the risks posed by Delta in Italy until recently, describing its presence as “rare” in the country in the official data monitoring report released on June 11th.

Health officials had said at the end of May that they believed vaccinations would be enough to mitigate the risks.

But Italy’s government is now re-evaluating its approach following criticism of its response so far in a report published on Thursday by independent health watchdog GIMBE.

“A ‘wait-and-see’ strategy on managing the Delta variant is unacceptable,” wrote GIMBE head Dr. Nino Cartabellotta.

MAP: Where is the Delta variant spreading in Italy?

Photo: Marco Bertorello/AFP

The report described Italy’s current levels of full vaccination coverage as “worrying” considering “the lower effectiveness of a single dose against this variant “.

At the moment, just over a quarter of the Italian population is fully vaccinated against Covid-19, compared to 46% in the United Kingdom.

The report pointed out that some 2.5 million people aged over 60 in Italy have not yet received the first dose of a vaccine.

The foundation urged the government to “properly implement” measures recommended by the ECDC in its report published earlier this week: “enhance sequencing and contact tracing, implement screening strategies for those arriving from abroad, and accelerate the administration of the second dose in over 60s”.

Cartabellotta said: “You can’t control the Covid pandemic only with vaccines, masks and distancing. Today the Delta variant requires tracing and sequencing”.

Amid rising concern about the impact of the variant, which is thought to increase the risk of hospitalisation, Italian health authorities on Monday imposed new travel restrictions on arrivals from the UK – almost a month after other EU countries including France and Germany did the same.

Despite concerns about the spread of Delta, Italian health authorities on Friday also confirmed that all regions of Italy would be allowed to ease the health measures further from Monday, June 28th, as the number of infections recorded remained low this week.

READ ALSO: Italy to drop outdoor mask-wearing rule from June 28th

The last region still classed as a ‘yellow’ zone, Valle d’Aosta, will join the rest of the country in the low-risk ‘white’ tier, meaning most rules can be relaxed.

“With the decree I just signed, all of Italy will be ‘white’ starting from Monday. It is an encouraging result, but we still need caution and prudence,” Speranza
wrote on Facebook.

Referring to the spread of more transmissible variants of the coronavirus, the minister added: “the battle has not yet been won.”

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