Four people travelling in the vehicles were detained last week in the Drome department in southeast France and charged with drug possession and distribution, among other offenses, said a statement.
A handgun was also found during the searches.
The haul — weighing more than 540 kilos — represents two-thirds of the drug typically seized in France in a year, and is worth around €10 million, according to the interior ministry.
The bust was the result of an investigation launched in October following the suspicious use of a rented vehicle in the southeastern department of Isere.
In April, investigators had detected preparations that appeared to point to a drug transporting operation from the north of France.
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