US businessman Paul Kaufmann donated the fragments, which he inherited, to the Medical University of Vienna where researchers will probe the illnesses suffered by the impresario and his cause of death.

“This is where the bones belong, back in Vienna,” Kaufmann told reporters.

Austrian coroner Christian Reiter said the 10 fragments, including two bigger pieces, one from the back of the head and one from the right side of the forehead, had “great value”.

“We have received really valuable material here, with which we hope to continue to research in the next years. That was Beethoven’s wish too,” Reiter said.

The composer battled illness throughout his life and explicitly asked for his body to be studied, Reiter added.

Beethoven, whose piano, chamber and symphonic works are among the greatest of Western classical music, died at 56 in 1827 after years of struggling with unknown ailments, including increasing deafness in his later years.

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The fragments are believed to be the only surviving fragments of Beethoven’s skull, Reiter added.

Kaufmann – whose Jewish ancestors fled the Nazis – said he found the fragments in a small box with “Beethoven” scratched on it in a family safety deposit box in a French bank in 1990.

Kaufmann’s great-great uncle, Austrian doctor Franz Romeo Seligmann, is presumed to have acquired them in 1863 during the exhumation of Beethoven’s body.

Kaufmann said the fragments would now be analysed further to confirm that they belong to the late composer, who died in Vienna.

 Cause of death a mystery

The available evidence suggests that they are authentic.

In 2005, a group of US scientists announced that tests on hair of Beethoven and the skull fragments showed he died from lead poisoning, which may have also been responsible for his hearing loss.

Researchers at the US Department of Energy’s Argonne National Laboratory in Illinois said the bone fragments, tested at the country’s most powerful X-ray facility, had high concentrations of lead, matching earlier findings of lead in his hair.

The source of the lead is unknown, but they said it may have come from a wine goblet made with the metal.

Alternatively, some medical treatments in the 18th and 19th centuries made use of heavy metals like lead and mercury.

Beethoven suffered abdominal pains in his 20s which became progressively worse, and the composer saw a large number of physicians in search of a cure.

In March, researchers who sequenced Beethoven’s genome using authenticated hair samples said liver failure, or cirrhosis, was likely behind his death brought about by a number of factors, including alcohol consumption.