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UPDATE – Coronavirus: French health minister and WHO issue warning over taking anti-inflammatories

France's health minister Olivier Véran warned the public on Saturday that anti-inflammatories like ibuprofen and cortisone could be an aggravating factor in coronavirus infections.

UPDATE - Coronavirus: French health minister and WHO issue warning over taking anti-inflammatories
Photo: AFP

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“Taking anti-inflammatories (ibuprofen, cortisone…) could be an aggravating factor for the infection,” Véran tweeted.

“In case of fever take paracetamol. If you are already on a course of anti-inflammatories or if you are in doubt then consult your doctor,” Véran added on Twitter.

His tweet was rapidly retweeted thousands of times with many members of the public asking for further information and a source for his reasoning.

France recently tightened the sale of ibuprofen and paracetamol due to the potential dangers associated with the drugs. The drugs are only sold behind the counter in pharmacies.

Paracetamol must be taken strictly according to the dose, because too high a dosage can be very dangerous for the liver.

Since the announcement the French government has decided to limit the sale of paracetamol in pharmacies due to a rise in demand.

From now on people without symptoms will only be able to buy one box and anyone with sympoms can buy two.

According to Le Figaro newspaper ibuprofen can aggravate existing infections that can lead to “complications”.

The newspaper continues: “Inflammation is a normal response from body to infection and it's an alert signal.

“By masking the response of the immune system taking anti-inflammatories can not only impair the body's response but also hide the signs of how serious it can be. This can delay the diagnosis and therefor treatment.”

According to Dr Annie Pierre from the centre of pharmacovigilance in Tours: “tests in animals showed that taking ibuprofen encourages the growth of certain bacteria.”

Last April France's Medicine's agency ANSM released a report that suggested anti-inflammatories had an aggravating role when it comes to infections.”

The French Minister's advice was then backed up by the WHO on March 17th.

The World Health Organization recommended Tuesday that people suffering from COVID-19-like symptoms should avoid self-medicating with ibuprofen.

The warnings followed a recent study in The Lancet weekly medical journal that hypothesised 
that an enzyme that is boosted when taking anti-inflammatory drugs like ibuprofen could facilitate and worsen COVID-19 infections.

Asked about the study, WHO spokesman Christian Lindmeier told reporters in Geneva that the UN health agency's experts were “looking into this to give further guidance.”

“In the meantime, we recommend using rather paracetamol, and do not use ibuprofen as a self-medication. That's important,” he said

On Friday France's Health Minister Veran said: “The spread of the virus across our territory is accelerating, especially in certain regions.”

He urged the public to limit contact and travel and to wash hands regularly as the death toll ion the country rose to 79.

“Respect social distancing, acknowledge someone rather than greet them physically, keep a metre distance and limit non-essential travel as well visits to the most vulnerable,” he said.

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HEALTH

France reports nearly 200 cholera cases in Mayotte

Nearly 200 cases of cholera have been reported on the French Indian Ocean island of Mayotte, which is struggling to contain the deadly epidemic.

France reports nearly 200 cholera cases in Mayotte

“As of June 18th, 2024, 193 cases of cholera have been reported in Mayotte,” France’s Santé publique France health agency reported in its weekly update.

Of those, 172 were locally acquired cases, while 21 were in people infected in the neighbouring Comoros archipelago and countries on the African continent.

Cholera is an infectious disease typically causing severe diarrhoea, vomiting and muscle cramps. It spreads easily in unsanitary conditions.

Mayotte, which is home to around 320,000 people, reported its first locally acquired cases of cholera in late April, according to officials in Paris.

Two people have died since the beginning of the epidemic, one of them a three-year-old girl.

Santé publique France warned there was a particularly high risk of transmission in disadvantaged neighbourhoods, “as long as access to drinking water and sanitation is unsatisfactory”.

French authorities have been criticised for failing to secure access to drinking water to prevent a cholera epidemic in its overseas territory.

President Emmanuel Macron called for cholera to be ‘consigned to the past’ when he hosted a summit on Thursday on vaccine production in Africa.

Many parts of Africa have recently seen fatal outbreaks of cholera, which has highlighted the shortage of local vaccine production.

The Comoros, which has been affected by a cholera epidemic for the past four months, has recorded 134 deaths and more than 8,700 cases, according to a report published by local authorities this month.

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