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MILAN

Medics fight to save baby in dead mother’s womb

Doctors in Milan are battling to save the life of an unborn baby by keeping his mother's heart beating for another month, despite her being brain dead. An expert told The Local the case is "incredibly rare".

Medics fight to save baby in dead mother's womb
Doctors hope to bring the pregnancy to 28 weeks. Baby photo: Shutterstock

The 36-year-old pregnant woman was pronounced clinically dead after being rushed to hospital last Tuesday following a brain hemorrhage, Corriere della Sera reported.

But doctors at the San Raffaele hospital have agreed with the woman’s family to keep her on life support, in the hope of saving her unborn child.

The baby, a boy, had little chance of survival when his mother died at 23 weeks pregnant. As a result doctors are keeping the woman in the intensive care unit until the 28th week of pregnancy, when they plan to perform a cesarean.

By then the baby’s organs would have formed and he will weigh around a kilo.

He will have developed enough to survive despite being well under the 40-week term of a usually pregnancy.

While medical equipment keeps the mother breathing and her blood flowing, a tube to the woman’s intestines is keeping the fetus fed.

The technique has succeeded in the past. In 1993, a “bouncing baby boy” was born over a hundred days after his mother was shot dead in the US.

Trisha Marshall was just 17 weeks pregnant when she died, but doctors kept the fetus alive for three months in her womb, LA Times wrote at the time.

Speaking to The Local on Friday, Dr Andrew Shennan, professor of obstetrics at Kings College London, said that the case was “incredibly rare”, although he had heard of similar cases in the past.

“The issue in this situation is to maintain the mother’s health sufficiently so that the baby can benefit from staying inside the womb and can mature safely and grow,” he said.

“But at the same time it depends on the complication with the mother as she may get infections or other things could go wrong.”

But, he added, the more challenging issues in this situation are ethical.

“Generally speaking you would act in the mother’s interest while she is pregnant so the mother’s life would always take precedence and babies are sometimes delivered in order to resuscitate mothers at the baby’s expense,” Dr Shennan said.

However, he added that in the situation where the mother is brain dead and has not made her intentions clear then doctors can only do what they believe she would want.

This is often decided by talking to the woman’s relatives, he said.  

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SCIENCE

Nobel Prize in Chemistry awarded for ‘ingenious tool for building molecules’

The Royal Swedish Academy of Sciences in Stockholm, responsible for awarding the Nobel Physics and Chemistry Prizes, has announced the winners of the 2021 Nobel Prize in Chemistry.

Peter Somfai, Member of the Nobel Committee for Chemistry, announces the winners for the 2021 Nobel Prize in Chemistry.
Peter Somfai, Member of the Nobel Committee for Chemistry, announces the 2021 winners. Photo: Claudio Bresciani

The prize this year has been awarded to Germany’s Benjamin List and David MacMillan from Scotland, based in the US.

The Nobel Committee stated that the duo were awarded the prize “for their development of a precise new tool for molecular construction: organocatalysis”. The committee further explained that this tool “has had a great impact on pharmaceutical research, and has made chemistry greener”.

Their tool, which they developed independently of each other in 2000, can be used to control and accelerate chemical reactions, exerting a big impact on drugs research. Prior to their work, scientists believed there were only two types of catalysts — metals and enzymes.

The new technique, which relies on small organic molecules and which is called “asymmetric organocatalysis” is widely used in pharmaceuticals, allowing drug makers to streamline the production of medicines for depression and respiratory infections, among others. Organocatalysts allow several steps in a production process to be performed in an unbroken sequence, considerably reducing waste in chemical manufacturing, the Nobel committee at the Royal Swedish Academy of Sciences said.

The Nobel committee gave more information in a press release as to why List and MacMillan were chosen: “Organocatalysis has developed at an astounding speed since 2000. Benjamin List and David MacMillan remain leaders in the field, and have shown that organic catalysts can be used to drive multitudes of chemical reactions. Using these reactions, researchers can now more efficiently construct anything from new pharmaceuticals to molecules that can capture light in solar cells. In this way, organocatalysts are bringing the greatest benefit to humankind.”

List and MacMillan, both 53, will share the 10-million-kronor prize.

“I thought somebody was making a joke. I was sitting at breakfast with my wife,” List told reporters by telephone during a press conference after the prize was announced. In past years, he said his wife has joked that he should keep an eye on his phone for a call from Sweden. “But today we didn’t even make the joke,” List said. “It’s hard to describe what you feel in that moment, but it was a very special moment that I will never forget.”

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