Roberto Pannunzi, who is wanted in Italy on drug trafficking charges, was detained in a Bogota shopping center with the help of the US Drug Enforcement Administration (DEA), the ministry said in a statement.
"When he was captured, Pannunzi identified himself with a fake Venezuelan identification card bearing the name Silvano Martino," it said.
The statement said Pannunzi is the "chief of the 'Ndrangheta criminal organization."
In April, Colombia captured another suspected top Italian mafia member, Domenico Trimboli, alleged to be a lynchpin between the Medellin drug cartel and the 'Ndrangheta, which is based in the Calabria region in southern Italy.
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