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Drug giant Roche posts strong profit rise

Swiss drug maker Roche posted a seven percent rise in its 2011 net profit to 9.5 billion francs ($10.3
billion) on Wednesday, despite the impact of the strong currency against the dollar and euro.

The performance was slightly up on analysts expectations who had predicted a figure of 9.3 billion francs, the AWP finance agency reported.

Operating profit dropped nine percent to 15.1 billion francs due to the negative effect of the exchange rate but increased six percent at constant rates.

Group sales went down 10 percent to 42.5 billion francs, the pharmaceutical giant said in a statement.

The strengthening of the Swiss franc against the dollar and the euro had a “significant negative impact” on the results expressed in Swiss francs, the group said.

“However the underlying currency translation exposure arising from non-Swiss franc revenues is significantly mitigated by the majority of the groups cost base (80 percent) being located outside Switzerland,” it said.

“We achieved our sales and earnings targets for the year and also made significant progress with our pipeline,” said chief executive Severin Schwan.

The company head said Roche was continuing to build its business with new products, highlighting 17 “positive” advanced clinical trials last year.

The board proposed a dividend increase of three percent to 6.80 Swiss francs.

For 2012 Roche forecast low to mid single-digit growth in sales at constant exchange rates and a high single-digit increase in core earnings per share.

Roche announced last week the launch of a $5.7 billion hostile takeover bid for Illumina, a US company specialising in gene sequencing.

On Tuesday the firm said it intended to nominate a list of “highly-qualified, independent” candidates for election to Illumina’s board to fill the seats of four departing directors.

It also wants to increase the board’s size from nine to 11 directors to give it a majority presence.

Illumina president and chief executive Jay Flatley said the board would advise stockholders of its position regarding the takeover bid next week.

“Our highly qualified board will continue to act independently and in the best interests of stockholders,” said Flatley in a statement.

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ROCHE

Swiss-American antibody drug ‘effective at preventing Covid infection’

US biotech firm Regeneron and its Swiss partner Roche unveiled promising clinical trial results Monday indicating that an antibody treatment used to treat Covid-19 patients also helps prevent infections.

Swiss-American antibody drug 'effective at preventing Covid infection'
Photo: Fabrice COFFRINI / AFP

The results of the Phase 3 trial showed that the combination of the antibodies casirivimab and imdevimab dramatically reduced the risk of symptomatic infection among people living with Covid-19 patients, Roche said in a statement.

The trial entailed injecting 1,505 people not infected with the SARS-CoV-2 virus but living in households with people carrying the virus with the Regeneron antibody cocktail or a placebo.

READ MORE: Why are vaccination appointments still vacant in Zurich?

The trial, which was conducted in cooperation with the National Institute of Allergy and Infectious Diseases, showed that those who received the antibody cocktail saw their risk of symptomatic infection reduced by 81 percent, the companies said.

It also indicated that those treated with casirivimab and imdevimab who did experience symptomatic infection on average saw their symptoms clear within one week — far faster than the three-week average for those who received the placebo.

In a separate part of the study, 204 people who had recently tested positive for Covid-19 but showed no symptoms received either a dose of the antibody cocktail or a placebo.

Those who received the cocktail saw their risk of developing symptoms reduced by 31 percent compared to the placebo group, the companies said.

“Today’s data confirm the potential dual value of casirivimab and imdevimab to reduce household Covid-19 infections and to decrease the disease burden in those who do become infected, when given as a subcutaneous option,” Levi Garraway, Roche’s chief medical officer said in a statement.

“Although vaccinations are increasing globally, there remains a critical unmet need worldwide to prevent infections and provide immediate protection from Covid-19 between close contacts,” he said.

EXPLAINED: How Switzerland is speeding up its vaccination programme

Regeneron president and chief scientist George Yancopoulos agreed, pointing out that in the United States alone, 60,000 people are being diagnosed with Covid-19 every day.

The antibody cocktail “may help provide immediate protection to unvaccinated people who are exposed to the virus”, he said in a statement, adding that it could also potentially “provide ongoing protection for immunocompromised patients who may not respond well to vaccines”.

Regeneron said it would present the data to the US Food and Drug Administration and request it clear the Covid antibody cocktail for use as a preventative treatment.

The companies said they would share the new data with health regulators worldwide.

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